RESEARCH ARTICLES
Shuang Wu, Kah Junn Tan, Lakshmi Narasimhan Govindarajan, James Charles Stewart, Lin Gu, Joses Wei Hao Ho, Malvika Katarya, Boon Hui Wong, Eng King Tan, Daiqin Li, Adam Claridge-Chang, Camilo Libedinsky, Li Cheng* and Sherry Shiying Aw*#
Automated leg tracking reveals distinct conserved gait and tremor signatures in Drosophila models of Parkinson’s Disease and Spinocerebellar ataxia 3. (In press, PLOS Biology)
bioRxiv 425405; doi: https://doi.org/10.1101/425405 (Click to view preprint)
(Github link to download FLLIT)
*Corresponding authors #Lead contact
Aw, S. *#, Lim, KH, Tang, XM, Cohen, SM*. (2017)
A glio-protective role of mir-263a by tuning sensitivity to glutamate.
Cell Reports 19(9): 1783–93 (Click to view)
*Corresponding authors #Lead contact
Aw, S.*#, Tang, XM., Teo, YN*, Cohen, SM., (2016)
A conformation-induced fluorescence method for microRNA detection.
Nucleic Acids Research 44 (10): e92, doi: 10.1093/nar/gkw108 (Click to view)
*Corresponding authors #Lead contact
Koe CT, Li S, Rossi F, Wong JJ, Wang Y, Zhang Z, Chen K, Aw SS, Richardson HE, Robson P, Sung WK, Yu F, Gonzalez C, Wang H. (2014)
The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages.
Elife 2014 Mar 11;3:e01906. doi: 10.7554/eLife.01906.
Li S, Wang C, Sandanaraj E, Aw SS, Koe CT, Wong JJ, Yu F, Ang BT, Tang C, Wang H. (2014)
The SCFSlimb E3 ligase complex regulates asymmetric division to inhibit neuroblast overgrowth.
EMBO Reports 15(2):165-74
Pai, V.*, Aw, S.*, Shomrat, T., Lemire, J., Levin, M. (2012)
Transmembrane Voltage Potential Controls Embryonic Eye Patterning in Xenopus laevis.
Development 139(2):313-23
* Equal contribution
Aw, S., Koster, J., Pearson, W., Nichols, C. Shi, N.Q., Carneiro de Paula, K. and Levin, M. (2010)
The ATP-sensitive K(+)-channel (K(ATP)) controls early left-right patterning in Xenopus and chick embryos.
Developmental Biology 1;346(1):39-53
Aw, S., Adams, D. S., Qiu, D., and Levin, M., (2008)
H,K-ATPase protein localization and Kir4.1 function reveal concordance of 3 axes during early determination of left-right asymmetry. Mechanisms of Development 125: 353-372
REVIEW ARTICLES
Sherry Aw and Stephen Cohen (2012)
Time is of the essence: microRNAs and age-associated neurodegeneration.
Cell Research 22(8):1218-20
Sherry Aw and Michael Levin (2009)
Is left-right asymmetry a form of planar cell polarity?
Development 136:355-366
Sherry Aw and Michael Levin (2008)
What’s Left in Asymmetry?
Developmental Dynamics 237: 3453-3463
BOOK CHAPTERS
Aw S. and Levin M, (2009), Molecular mechanisms establishing consistent left–right asymmetry during vertebrate embryogenesis. The Sinister Right Hemisphere: Cerebral lateralization and its possible role in psychosis, ed. Iris E. C. Sommer and René S. Khan. Published by Cambridge University Press
PATENTS
A simple one-step real-time molecular sensor for microRNA detection
Provisional Patent #10201601384T - IMC/P/08599/01/SG 2014
PCT patent - PCT/SG2017/050086 2017
An automated method for leg movement tracking in Drosophila 2017
(Singapore provisional patent #10201707833S)(Not converted)
Shuang Wu, Kah Junn Tan, Lakshmi Narasimhan Govindarajan, James Charles Stewart, Lin Gu, Joses Wei Hao Ho, Malvika Katarya, Boon Hui Wong, Eng King Tan, Daiqin Li, Adam Claridge-Chang, Camilo Libedinsky, Li Cheng* and Sherry Shiying Aw*#
Automated leg tracking reveals distinct conserved gait and tremor signatures in Drosophila models of Parkinson’s Disease and Spinocerebellar ataxia 3. (In press, PLOS Biology)
bioRxiv 425405; doi: https://doi.org/10.1101/425405 (Click to view preprint)
(Github link to download FLLIT)
*Corresponding authors #Lead contact
Aw, S. *#, Lim, KH, Tang, XM, Cohen, SM*. (2017)
A glio-protective role of mir-263a by tuning sensitivity to glutamate.
Cell Reports 19(9): 1783–93 (Click to view)
*Corresponding authors #Lead contact
Aw, S.*#, Tang, XM., Teo, YN*, Cohen, SM., (2016)
A conformation-induced fluorescence method for microRNA detection.
Nucleic Acids Research 44 (10): e92, doi: 10.1093/nar/gkw108 (Click to view)
*Corresponding authors #Lead contact
Koe CT, Li S, Rossi F, Wong JJ, Wang Y, Zhang Z, Chen K, Aw SS, Richardson HE, Robson P, Sung WK, Yu F, Gonzalez C, Wang H. (2014)
The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages.
Elife 2014 Mar 11;3:e01906. doi: 10.7554/eLife.01906.
Li S, Wang C, Sandanaraj E, Aw SS, Koe CT, Wong JJ, Yu F, Ang BT, Tang C, Wang H. (2014)
The SCFSlimb E3 ligase complex regulates asymmetric division to inhibit neuroblast overgrowth.
EMBO Reports 15(2):165-74
Pai, V.*, Aw, S.*, Shomrat, T., Lemire, J., Levin, M. (2012)
Transmembrane Voltage Potential Controls Embryonic Eye Patterning in Xenopus laevis.
Development 139(2):313-23
* Equal contribution
Aw, S., Koster, J., Pearson, W., Nichols, C. Shi, N.Q., Carneiro de Paula, K. and Levin, M. (2010)
The ATP-sensitive K(+)-channel (K(ATP)) controls early left-right patterning in Xenopus and chick embryos.
Developmental Biology 1;346(1):39-53
Aw, S., Adams, D. S., Qiu, D., and Levin, M., (2008)
H,K-ATPase protein localization and Kir4.1 function reveal concordance of 3 axes during early determination of left-right asymmetry. Mechanisms of Development 125: 353-372
REVIEW ARTICLES
Sherry Aw and Stephen Cohen (2012)
Time is of the essence: microRNAs and age-associated neurodegeneration.
Cell Research 22(8):1218-20
Sherry Aw and Michael Levin (2009)
Is left-right asymmetry a form of planar cell polarity?
Development 136:355-366
Sherry Aw and Michael Levin (2008)
What’s Left in Asymmetry?
Developmental Dynamics 237: 3453-3463
BOOK CHAPTERS
Aw S. and Levin M, (2009), Molecular mechanisms establishing consistent left–right asymmetry during vertebrate embryogenesis. The Sinister Right Hemisphere: Cerebral lateralization and its possible role in psychosis, ed. Iris E. C. Sommer and René S. Khan. Published by Cambridge University Press
PATENTS
A simple one-step real-time molecular sensor for microRNA detection
Provisional Patent #10201601384T - IMC/P/08599/01/SG 2014
PCT patent - PCT/SG2017/050086 2017
An automated method for leg movement tracking in Drosophila 2017
(Singapore provisional patent #10201707833S)(Not converted)